Mindfulness meditation uses distinct neural pathways to reduce pain better than placebo

Thomas Rosenthal, Pain Medicine News: Recent research showed that mindfulness meditation is significantly more effective at reducing pain intensity and pain unpleasantness than placebo analgesia, sham mindfulness meditation and other cognitive-based approaches by using distinct neural mechanisms (J Neurosci 2015;35:15307-15325).

“This study is the first to demonstrate that mindfulness-related pain relief is mechanistically distinct from placebo analgesia,” the researchers wrote. “The elucidation of this distinction confirms the existence of multiple, cognitively driven, supraspinal mechanisms for pain modulation.” Specifically, mindfulness meditation–induced pain relief was associated with greater neural activation in higher-order …

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