UCLA

Mindfulness meditation: Key to a longer, stress-free life?

Oliver Ubeda, Synapse: During my first year of pharmacy school, I attended an alternative medicine Saturday elective where Dr. Dean Ornish spoke about the benefits of meditation and the effect it has on lengthening our chromosomal telomeres.

Telomeres are portions of repetitive DNA at the ends of our chromosomes that protect our chromosomes from deteriorating.

Meditation was the focus of research at UC Davis and UCSF by Nobel Prize winner Elizabeth Blackburn, PhD, and others as part of the Shamatha project.

The 2011 study found that meditation increased activity of telomerase — enzymes that can rebuild and lengthen our chromosomal telomeres…

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Mindfulness, being in the moment, is now of the moment

Mary MacVean, Los Angeles Times: Every Thursday at lunchtime at the Hammer Museum in Westwood, several dozen people turn off their cellphones and take seats in the bright pink chairs of the Billy Wilder Theater.

They come to spend half an hour with Diana Winston, a former Buddhist nun and one of the nation’s best-known teachers of mindfulness meditation. The lights go down, and Winston takes a seat in an office chair and speaks quietly into a microphone.

Occasionally she is accompanied by a guest playing about 20 Tibetan bells, the haunting, wave-like sounds enhancing her voice, which is so soothing it’s as if …

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Yoga reduces inflammation response

UCLA study helps caregivers of people with dementia

Six months ago, researchers at UCLA published a study that showed using a specific type of yoga to engage in a brief, simple daily meditation reduced the stress levels of people who care for those stricken by Alzheimer’s and dementia. Now they know why.

As previously reported, practicing a certain form of chanting yogic meditation for just 12 minutes daily for eight weeks led to a reduction in the biological mechanisms responsible for an increase in the immune system’s inflammation response. Inflammation, if constantly activated, can contribute to a multitude of chronic health problems.

Reporting in the current online edition of the journal Psychoneuroendocrinology, Dr. Helen Lavretsky, senior author and a professor of psychiatry at the UCLA Semel Institute for Neuroscience and Human Behavior, and colleagues found in their work with 45 family dementia caregivers that 68 of their genes responded differently after Kirtan Kriya Meditation (KKM), resulting in reduced inflammation.

Caregivers are the unsung heroes for their yeoman’s work in taking care of loved ones that have been stricken with Alzheimer’s and other forms of dementia, said Lavretsky, who also directs UCLA’s Late-Life Depression, Stress and Wellness Research Program. But caring for a frail or demented family member can be a significant life stressor. Older adult caregivers report higher levels of stress and depression and lower levels of satisfaction, vigor and life in general. Moreover, caregivers show higher levels of the biological markers of inflammation. Family members in particular are often considered to be at risk of stress-related disease and general health decline.

As the U.S. population continues to age over the next two decades, Lavretsky noted, the prevalence of dementia and the number of family caregivers who provide support to these loved ones will increase dramatically. Currently, at least five million Americans provide care for someone with dementia.

“We know that chronic stress places caregivers at a higher risk for developing depression,” she said “On average, the incidence and prevalence of clinical depression in family dementia caregivers approaches 50 percent. Caregivers are also twice as likely to report high levels of emotional distress.” What’s more, many caregivers tend to be older themselves, leading to what Lavretsky calls an “impaired resilience” to stress and an increased rate of cardiovascular disease and mortality.

Research has suggested for some time that psychosocial interventions like meditation reduce the adverse effects of caregiver stress on physical and mental health. However, the pathways by which such psychosocial interventions impact biological processes are poorly understood.

In the study, the participants were randomized into two groups. The meditation group was taught the 12-minute yogic practice that included Kirtan Kriya, which was performed every day at the same time for eight weeks. The other group was asked to relax in a quiet place with their eyes closed while listening to instrumental music on a relaxation CD, also for 12 minutes daily for eight weeks. Blood samples were taken at the beginning of the study and again at the end of the eight weeks.

“The goal of the study was to determine if meditation might alter the activity of inflammatory and antiviral proteins that shape immune cell gene expression,” said Lavretsky. “Our analysis showed a reduced activity of those proteins linked directly to increased inflammation.

“This is encouraging news. Caregivers often don’t have the time, energy, or contacts that could bring them a little relief from the stress of taking care of a loved one with dementia, so practicing a brief form of yogic meditation, which is easy to learn, is a useful too.”

Lavretsky is a member of UCLA’s recently launched Alzheimer’s and Dementia Care Program, which provides comprehensive, coordinated care as well as resources and support to patients and their caregivers. Lavretsky has incorporated yoga practice into the caregiver program.

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In sitting still, a bench press for the brain

John Hanc, New York Times: In 1969, Katherine Splain, then a student at the College of New Rochelle, saw the dark side of drug use among her peers. So she sought a different — and legal — path on her inward journey.

“I had read that meditation was actually another way of achieving the kind of ‘high’ that you might experience if you did drugs,” said Ms. Splain, who is now 63.

She heard about a class in meditation being offered near the school, decided to visit and was impressed with the students she met. “There wasn’t a lot of peace in the world in 1969 …

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UCLA research scientist to explain benefits of meditation in Saratoga

Saturday, Apr 7 10:30 am to 12:00 noon, at West Valley College, Saratoga, CA.

Price: $12

Phone: (408) 702-2319

Join UCLA behavioral research scientist, Dara Ghahremani & National Director of the Art of Meditation, Rajshree Patel as they explore how we can tune back into ourselves despite the daily demands in a stressful environment.

Rajshree Patel, known for her intellect, humor and dynamism, will share insights on how to handle mental chatter through meditation. As a former Los Angeles district attorney she accidentally walked into a meditation workshop. After she started her meditation practice, she discovered that she could handle twice the number of cases as compared to her peers in lesser amount of time and was much more productive. Dara Ghahremani with his crispness and intelligence is sure to feed your intellectual curiosity about the science of the brain and meditation. As a leading researcher at UCLA Center for Addictive Behavior his tidbits about research on meditation tools is sure to coax anyone to explore the depth of ones’ own mind.

The experience of the deep silence, during a live meditation, in a large audience, is sure to amaze you. Take a step towards taking charge of your own wellness, on World health day 2012, with the incredible guided meditation session to be led by Rajshree Patel.

[via Mercury News]
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Research reveals meditation changes brain

Denise Dador, KABC: Over the years, numerous studies have shown how meditation can be a great way to manage and alleviate stress. Now local researchers say there appears to be physical proof that shows years of meditation may change the brain.

Meditation trainer Julianna Raye of Hollywood is guiding a mindfulness exercise. She’s been practicing for 17 years and says it’s made her mind stronger.

“It’s like training at the gym,” said Raye. “You’re training your mind. You’re improving your concentration. And that’s a skill that you need to develop.”

Raye may be using building muscles …

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More evidence emerges that meditation strengthens the brain

Earlier evidence out of UCLA suggested that meditating for years thickens the brain (in a good way) and strengthens the connections between brain cells.

Now a further report by UCLA researchers suggests yet another benefit.

Eileen Luders, an assistant professor at the UCLA Laboratory of Neuro Imaging, and colleagues, have found that long-term meditators have larger amounts of gyrification (“folding” of the cortex, which may allow the brain to process information faster) than people who do not meditate.

Further, a direct correlation was found between the amount of gyrification and the number of meditation years, possibly providing further proof of the brain’s neuroplasticity, or ability to adapt to environmental changes.

The article appears in the online edition of the journal Frontiers in Human Neuroscience.

The cerebral cortex is the outermost layer of neural tissue. Among other functions, it plays a key role in memory, attention, thought and consciousness. Gyrification or cortical folding is the process by which the surface of the brain undergoes changes to create narrow furrows and folds called sulci and gyri. Their formation may promote and enhance neural processing. Presumably then, the more folding that occurs, the better the brain is at processing information, making decisions, forming memories and so forth.

“Rather than just comparing meditators and non-meditators, we wanted to see if there is a link between the amount of meditation practice and the extent of brain alteration,” said Luders. “That is, correlating the number of years of meditation with the degree of folding.”

Of the 49 recruited subjects, the researchers took MRI scans of 23 meditators and compared them to 16 control subjects matched for age, handedness and sex. (Ten participants dropped out.) The scans for the controls were obtained from an existing MRI database, while the meditators were recruited from various meditation venues. The meditators had practiced their craft on average for 20 years using a variety of meditation types — Samatha, Vipassana, Zen and more. The researchers applied a well-established and automated whole-brain approach to measure cortical gyrification at thousands of points across the surface of the brain.

They found pronounced group differences (heightened levels of gyrification in active meditation practitioners) across a wide swatch of the cortex, including the left precentral gyrus, the left and right anterior dorsal insula, the right fusiform gyrus and the right cuneus.

Perhaps most interesting, though, was the positive correlation between the number of meditation years and the amount of insular gyrification.

“The insula has been suggested to function as a hub for autonomic, affective and cognitive integration,” said Luders. “Meditators are known to be masters in introspection and awareness as well as emotional control and self-regulation, so the findings make sense that the longer someone has meditated, the higher the degree of folding in the insula.”

While Luders cautions that genetic and other environmental factors could have contributed to the effects the researchers observed, still, “The positive correlation between gyrification and the number of practice years supports the idea that meditation enhances regional gyrification.”

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Donna Karan begins yoga, meditation program at UCLA hospital

Sarah Fay: Patients and staff at Ronald Reagan UCLA Medical Center will be the first on the west coast to receive training in a blend of Eastern and Western therapies designed by yoga instructors and fashion designer Donna Karan.

Urban Zen Foundation, started by Karan, is taking up residency at UCLA to ease the minds and bodies of cancer patients and their caretakers. It is the first hospital on the west coast to adopt the program, which involves training in yoga, Reiki, meditation, aromatherapy and other practices. Karan was at UCLA Thursday to visit with patients and staff.

“People think yoga is kind of …

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Is meditation the push-up for the brain?

Study shows practice may have potential to change brain’s physical structure

Two years ago, researchers at UCLA found that specific regions in the brains of long-term meditators were larger and had more gray matter than the brains of individuals in a control group. This suggested that meditation may indeed be good for all of us since, alas, our brains shrink naturally with age.

Now, a follow-up study suggests that people who meditate also have stronger connections between brain regions and show less age-related brain atrophy. Having stronger connections influences the ability to rapidly relay electrical signals in the brain. And significantly, these effects are evident throughout the entire brain, not just in specific areas.

Eileen Luders, a visiting assistant professor at the UCLA Laboratory of Neuro Imaging, and colleagues used a type of brain imaging known as diffusion tensor imaging, or DTI, a relatively new imaging mode that provides insights into the structural connectivity of the brain. They found that the differences between meditators and controls are not confined to a particular core region of the brain but involve large-scale networks that include the frontal, temporal, parietal and occipital lobes and the anterior corpus callosum, as well as limbic structures and the brain stem.

The study appears in the current online edition of the journal NeuroImage.

“Our results suggest that long-term meditators have white-matter fibers that are either more numerous, more dense or more insulated throughout the brain,” Luders said. “We also found that the normal age-related decline of white-matter tissue is considerably reduced in active meditation practitioners.”

The study consisted of 27 active meditation practitioners (average age 52) and 27 control subjects, who were matched by age and sex. The meditation and the control group each consisted of 11 men and 16 women. The number of years of meditation practice ranged from 5 to 46; self-reported meditation styles included Shamatha, Vipassana and Zazen, styles that were practiced by about 55 percent of the meditators, either exclusively or in combination with other styles.

Results showed pronounced structural connectivity in meditators throughout the entire brain’s pathways. The greatest differences between the two groups were seen within the corticospinal tract (a collection of axons that travel between the cerebral cortex of the brain and the spinal cord); the superior longitudinal fasciculus (long bi-directional bundles of neurons connecting the front and the back of the cerebrum); and the uncinate fasciculus (white matter that connects parts of the limbic system, such as the hippocampus and amygdala, with the frontal cortex).

“It is possible that actively meditating, especially over a long period of time, can induce changes on a micro-anatomical level,” said Luders, herself a meditator.

As a consequence, she said, the robustness of fiber connections in meditators may increase and possibly lead to the macroscopic effects seen by DTI.

“Meditation, however, might not only cause changes in brain anatomy by inducing growth but also by preventing reduction,” Luders said. “That is, if practiced regularly and over years, meditation may slow down aging-related brain atrophy, perhaps by positively affecting the immune system.”

But there is a “but.” While it is tempting to assume that the differences between the two groups constitute actual meditation-induced effects, there is still the unanswered question of nature versus nurture.

“It’s possible that meditators might have brains that are fundamentally different to begin with,” Luders said. “For example, a particular brain anatomy may have drawn an individual to meditation or helped maintain an ongoing practice — meaning that the enhanced fiber connectivity in meditators constitutes a predisposition towards meditation, rather than being the consequence of the practice.”

Still, she said, “Meditation appears to be a powerful mental exercise with the potential to change the physical structure of the brain at large. Collecting evidence that active, frequent and regular meditation practices cause alterations of white-matter fiber tracts that are profound and sustainable may become relevant for patient populations suffering from axonal demyelination and white-matter atrophy.”

But, Luders said, more research is needed before taking meditation into clinical trial studies.

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Meditation slows down age-related brain atrophy

Researchers at UCLA had earlier found that specific regions in the brains of long-term meditators were larger and had more grey matter than the brains of individuals in a control group.

Now, a follow-up study has suggested that people who meditate also have stronger connections between brain regions and show less age-related brain atrophy.

Having stronger connections influences the ability to rapidly relay electrical signals in the brain. And significantly, these effects are evident throughout the entire brain, not just in specific areas.

Eileen Luders, a visiting assistant professor at the UCLA Laboratory of Neuro Imaging, and colleagues found that the differences between meditators and controls are not confined to a particular core region of the brain but involve large-scale networks that include the frontal, temporal, parietal and occipital lobes and the anterior corpus callosum, as well as limbic structures and the brain stem.

“Our results suggest that long-term meditators have white-matter fibers that are either more numerous, more dense or more insulated throughout the brain,” said Luders.

“We also found that the normal age-related decline of white-matter tissue is considerably reduced in active meditation practitioners,” added Luders.

The study consisted of 27 active meditation practitioners (average age 52) and 27 control subjects. Results showed pronounced structural connectivity in meditators throughout the entire brain’s pathways.

“It is possible that actively meditating, especially over a long period of time, can induce changes on a micro-anatomical level,” said Luders.

As a consequence, she said, the robustness of fiber connections in meditators may increase and possibly lead to the macroscopic effects seen by DTI.

“Meditation, however, might not only cause changes in brain anatomy by inducing growth but also by preventing reduction,” said Luders.

“That is, if practiced regularly and over years, meditation may slow down aging-related brain atrophy, perhaps by positively affecting the immune system,” added Luders.

The study is detailed in the online edition of the journal NeuroImage.

Original article no longer available…

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